Progesterone and Luteal Phase Support in IVF
Progesterone is a hormone that prepares the uterine lining (endometrium) for an embryo to implant and supports early pregnancy. In IVF cycles the body's own release may not be enough, so extra progesterone is given.
This is called luteal phase support. The overview below explains why and how it is used.
Why is progesterone given?
The egg-retrieval step and the medications used can temporarily affect the body's own progesterone production. Support is given so the endometrium stays receptive for an embryo.
The aim is to keep the environment suitable for implantation and to support the early phase.
How is it used?
Progesterone can be given in different forms, and your doctor decides which suits you:
- Vaginal gel, pessary or capsule
- Intramuscular (injection) form
- Oral forms in some situations
When does it start and how long?
Support usually begins around egg retrieval or embryo transfer. If the pregnancy test is positive, it continues for a period your doctor defines.
The duration depends on the person and cycle type; never stop on your own, always ask your doctor.
Side effects and things to watch
Mild bloating, tenderness, dizziness or irritation at the application site can occur. These effects are usually temporary.
Using the medication regularly and as advised is one of the most important parts of the process.
Common mistakes
A few points are worth keeping in mind with luteal support:
- Not changing the dose or method on your own
- Not stopping before the test day
- Being consistent with timing
Related Reading
- After Embryo Transfer: Implantation Symptoms and What to Expect
- IVF Injections and Medications: The Process, Side Effects and Common Questions
- The Stages of IVF Treatment
Sources and references
This article is supported by the following independent, authoritative sources: